https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Peri-conception and first trimester diet modifies reproductive development in bulls https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:37825 n = 360) were individually fed a high- or low-protein diet (HPeri and LPeri) from 60 days before conception. From 24 until 98 days post conception, half of each treatment group changed to the alternative post-conception high- or low-protein diet (HPost and LPost) yielding four treatment groups in a 2 x 2 factorial design. A subset of male fetuses (n = 25) was excised at 98 days post conception and fetal testis development was assessed. Reproductive development of singleton male progeny (n = 40) was assessed until slaughter at 598 days of age, when adult testicular cytology was evaluated. Low peri-conception diet delayed reproductive development: sperm quality was lowered during pubertal development with a concomitant delay in reaching puberty. These effects were subsequent to lower FSH concentrations at 330 and 438 days of age. In the fetus, the low peri-conception diet increased the proportion of seminiferous tubules and decreased blood vessel area in the testis, whereas low first trimester diet increased blood vessel number in the adult testis. We conclude that maternal dietary protein perturbation during conception and early gestation may alter male testis development and delay puberty in bulls.]]> Tue 11 May 2021 15:20:38 AEST ]]> Adult body size, sexual history and adolescent sexual development, may predict risk of developing prostate cancer: results from the New South Wales Lifestyle and Evaluation of Risk Study (CLEAR) https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33342 Thu 28 Oct 2021 13:04:32 AEDT ]]> Distribution of ocular biometric parameters and refraction in a population-based study of Australian children https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:408 Thu 25 Jul 2013 09:09:51 AEST ]]> Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes. https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:54727 Mon 11 Mar 2024 14:11:41 AEDT ]]>